Should we apply suction during fine needle cytology of thyroid lesions? A systematic review and meta-analysis.

نویسندگان

  • David D Pothier
  • A A Narula
چکیده

INTRODUCTION Fine needle aspiration cytology (FNAC) is a well-established investigation in thyroid disease. Fine needle sampling without aspiration (FNS) is less commonly used but often easier to perform. Both methods have advantages and disadvantages but, as yet, there is no agreement on which method produces better specimens for cytological diagnosis. MATERIALS AND METHODS We undertook a review of the literature and performed a meta-analysis of the results of four cross-over trials. RESULTS The resulting odds ratio favoured FNS (OR = 0.99; 95% CI 0.88-1.11) but was not statistically significant. A fifth paper not included in the meta-analysis reported results in favour of FNS (P = 0.003). CONCLUSIONS There is no evidence from the meta-analysis that one method is superior to the other; however, taking into consideration all available evidence, it seems that FNS may be easier to perform and may produce better samples.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fine Needle Aspiration Cytology versus Fine Needle Capillary Sampling in Cytological Diagnosis of Thyroid Lesions

Background and Objectives: Fine needle aspiration cytology (FNAC) is an established out- patient procedure used in primary diagnosis of palpable thyroid lesions. A modified technique fine needle capillary sampling (FNCS) obviates the need of suction, is less painful, patient friendly and reported to overcome the problem of inadequate and bloody specimens. The aim of our study was to compare the...

متن کامل

Diagnostic Accuracy of Frozen Section in Comparison With Fine Needle Aspiration Cytology in Thyroid Lesions – A Prospective Study

Background and Objectives: Thyroid gland because of its superficial location is amenable to direct physical examination. Clinical assessment of thyroid lesions by means of physical examination, thyroid scans and ultrasonography is not completely reliable. Fine needle aspiration cytology (FNAC) is the most cost-effective, safe and an initial diagnostic test in the pre-operative evaluation of thy...

متن کامل

Comparision of the Diagnostic values of Doppler Sonography with Fine Needle Aspiration in Thyroid Nodules

Introduction: Thyroid nodules are frequent occurrences, and whenever diagnosed, it is necessary to rule out of malignancy. Valuable diagnostic methods in this field are sonography and fine needle aspiration. In this study while investigating these two methods, we compared them with postsurgical pathologic findings. Materials and methods: This is a cross sectional, descriptive-analytical study. ...

متن کامل

Diagnostic pitfalls of pilomatricoma on fine needle aspiration cytology

Pilomatricoma is a benign skin adnexal tumour usually seen in the head and neck region of children and young adults. It is underrecognized on cytology, resulting in the overdiagnosis of malignancy. We bring forth a case report of a slow growing nodular swelling in a 10-year-old female child, which was misdiagnosed on Fine Needle Aspiration Cytology (FNAC) as a malignant neoplasm and found to be...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Annals of the Royal College of Surgeons of England

دوره 88 7  شماره 

صفحات  -

تاریخ انتشار 2006